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Article

Functional polymorphisms of HSPA5: possible association with bipolar disorder.

Biochemical and biophysical research communications - 4 Nov 2005

Kakiuchi Chihiro, Ishiwata Mizuho, Nanko Shinichiro, Kunugi Hiroshi, Minabe Yoshio, Nakamura Kazuhiko, Mori Norio, Fujii Kumiko, Umekage Tadashi, Tochigi Mamoru, Kohda Kazuhisa, Sasaki Tsukasa, Yamada Kazuo, Yoshikawa Takeo, Kato Tadafumi

Abstract excerpt

Altered endoplasmic reticulum stress (ER) response signaling is suggested in bipolar disorder. Previously, we preliminarily reported the genetic association of HSPA5 (GRP78/BiP) with bipolar disorder. Here, we extended our analysis by increasing the number of Japanese case-control samples and NIMH Genetics Initiative bipolar trio samples (NIMH trios), and also analyzed schizophrenia samples. In Japanese,...

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Source

Identifiers

PMID: 16168956
DOI: 10.1016/j.bbrc.2005.08.248

Genes

HSPA5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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