Article
Examining the association of NRXN3 SNPs with borderline personality disorder phenotypes in heroin dependent cases and socio-economically disadvantaged controls.
Drug and alcohol dependence - 1 Mar 2013
Panagopoulos Vassilis N, Trull Timothy J, Glowinski Anne L, Lynskey Michael T, Heath Andrew C, Agrawal Arpana, Henders Anjali K, Wallace Leanne, Todorov Alexandre A, Madden Pamela A F, Moore Elizabeth, Degenhardt Louisa, Martin Nicholas G, Montgomery Grant W, Nelson Elliot C
Abstract excerpt
BACKGROUND: Borderline personality disorder (BPD) and substance use disorders frequently co-occur; their dual presence predicts poor prognosis. The genetic underpinnings of BPD have not been well-characterized and could offer insight into comorbidity. The current report focuses on the association of neurexin 3 (NRXN3) single nucleotide polymorphisms (SNPs) with BPD symptoms in heroin dependent cases and controls....
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