Article
[Bactericidal activity and capacity for selection of mutants resistant to imipenmen and meropenem in strains of Proteus, Morganella and Providencia].
Enfermedades infecciosas y microbiologia clinica - 1 Jan 2000
Villar H E, Longo L, Arena M F, Laurino G, Hoffman M
Abstract excerpt
BACKGROUND: To compare the bactericidal activity and frequency of mutation for meropenem and imipenem against Proteus mirabilis, Morganella morganii and Providencia rettgeri. MATERIAL AND METHODS: Minimum inhibitory concentrations (MIC) were determined by agar dilution method. Bactericidal activities were evaluated by killing curves method employing 4 and 16x MIC. One-step resistant mutant selection was performed...
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