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Article

TRIM22 genotype is not associated with markers of disease progression in children with HIV-1 infection.

AIDS (London, England) - 1 Dec 2021

Boswell Michael T, Yindom Louis-Marie, Hameiri-Bowen Dan, McHugh Grace, Dauya Ethel, Bandason Tsitsi, Mujuru Hilda, Esbjörnsson Joakim, Ferrand Rashida A, Rowland-Jones Sarah

Abstract excerpt

OBJECTIVE: Untreated perinatal HIV-1 infection is often associated with rapid disease progression in children with HIV (CWH), characterized by high viral loads and early mortality. TRIM22 is a host restriction factor, which directly inhibits HIV-1 transcription, and its genotype variation is associated with disease progression in adults. We tested the hypothesis that TRIM22 genotype is associated with disease...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34870928
DOI: 10.1097/QAD.0000000000003053
PMCID: PMC7614957

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