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Article

Transforming growth factor-beta gene polymorphisms in sarcoidosis patients with and without fibrosis.

Chest - 1 Jun 2006

Kruit Adrian, Grutters Jan C, Ruven Henk J T, van Moorsel Coline H M, Weiskirchen Ralf, Mengsteab Senait, van den Bosch Jules M M

Abstract excerpt

STUDY OBJECTIVES: Pulmonary fibrosis develops in approximately 25% of patients with chronic sarcoidosis. Transforming growth factor (TGF)-beta1 plays a central role in fibrosis, and accruing reports address the implication of TGF-beta2 and TGF-beta3 in this process. We determined whether single-nucleotide polymorphisms (SNPs) in the TGF-beta1, TGF-beta2, and TGF-beta3 genes might contribute to pulmonary fibrosis...

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Source

Identifiers

PMID: 16778279
DOI: 10.1378/chest.129.6.1584

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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