Article
Transforming growth factor-{beta} gene polymorphisms in different phenotypes of sarcoidosis.
The European respiratory journal - 1 Jul 2011
Pabst S, Fränken T, Schönau J, Stier S, Nickenig G, Meyer R, Skowasch D, Grohé C
Abstract excerpt
The aetiology of sarcoidosis is unclear. Single nucleotide polymorphisms (SNPs) in transforming growth factor (TGF)-β2 and -β3 have been reported to be associated with the development of lung fibrosis in patients with sarcoidosis. SNPs in TGF-β2 (rs1891467) and TGF-β3 (rs3917200) were investigated in 296 patients with sarcoidosis (acute/self remitting, n = 70 (including 62 patients with Löfgren's syndrome);...
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