Article
Activation of paternally expressed imprinted genes in newly derived germline-competent mouse parthenogenetic embryonic stem cell lines.
Cell research - 1 Sept 2007
Jiang Hua, Sun Bowen, Wang Weicheng, Zhang Zhihong, Gao Furong, Shi Guilai, Cui Bing, Kong Xiangyin, He Zhao, Ding Xiaoyan, Kuang Ying, Fei Jian, Sun Yi Juan, Feng Yun, Jin Ying
Abstract excerpt
Parthenogenetic embryonic stem (pES) cells provide a valuable in vitro model system for studying the molecular mechanisms that underlie genomic imprinting. However, the pluripotency of pES cells and the expression profiles of paternally expressed imprinted genes have not been fully explored. In this study, three mouse pES cell lines were established and the differentiation potential of these cells in extended...
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