Article
Characterization of human H1N1 influenza virus variants selected in vitro with zanamivir in the presence of sialic acid-containing molecules.
Virus research - 1 Nov 2007
Giannecchini Simone, Campitelli Laura, Bandini Giacomo, Donatelli Isabella, Azzi Alberta
Abstract excerpt
Understanding the molecular mechanisms of influenza virus resistance to neuraminidase inhibitors is a main concern for their clinical use. In an attempt to reproduce in vivo selective conditions where influenza virus resistance to neuraminidase inhibitors can occur the zanamivir selection of an A/H1N1 influenza virus strain was carried out in Madin-Darby canine kidney cells performed in the presence or absence of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
