Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterization of drug-resistant recombinant influenza A/H1N1 viruses selected in vitro with peramivir and zanamivir.

Antiviral research - 1 May 2007

Baz Mariana, Abed Yacine, Boivin Guy

Abstract excerpt

There is a limited information with regard to the neuraminidase (NA) mutations conferring resistance to peramivir and zanamivir in the influenza N1 background. In this study, an influenza A/WSN/33 (H1N1) recombinant virus was passaged under peramivir or zanamivir pressure. The peramivir-selected variant had a H274Y mutation in the neuraminidase (NA) gene conferring resistance to peramivir and oseltamivir but...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cyclopentanes
Share to Dogs
Share to Guanidines

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hemagglutinin Glycoproteins, Influenza Virus

Share to Influenza A Virus, H1N1 Subtype

Share to Neuraminidase

Share to Oseltamivir

Share to Zanamivir

Source

Identifiers

PMID: 17137644
DOI: 10.1016/j.antiviral.2006.10.012

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization of drug-resistant recombinant influenza A/H1N1 viruses selected in vitro with peramivir and zanamivir.PMID 17137644Read ↗

In vitro generation of neuraminidase inhibitor resistance in A(H5N1) influenza viruses.Semantic proximity Read ↗

Peramivir susceptibilities of recombinant influenza A and B variants selected with various neuraminidase inhibitors.Semantic proximity Read ↗

Influenza neuraminidase inhibitors: antiviral action and mechanisms of resistanceSemantic proximity Read ↗

Development of oseltamivir and zanamivir resistance in influenza A(H1N1)pdm09 virus, Denmark, 2014.Semantic proximity Read ↗

Mutations of neuraminidase implicated in neuraminidase inhibitors resistance.Semantic proximity Read ↗

Importance of neuraminidase active-site residues to the neuraminidase inhibitor resistance of influenza viruses.Semantic proximity Read ↗

Molecular pathway of influenza pan-neuraminidase inhibitors resistance in an immunocompromised patientSemantic proximity Read ↗

Detection and management of antiviral resistance for influenza virusesSemantic proximity Read ↗

Susceptibility of Brazilian influenza A(H1N1)pdm09 viruses to neuraminidase inhibitors in the 2014-2016 seasons: Identification of strains bearing mutations associated with reduced inhibition profile.Semantic proximity Read ↗

Neuraminidase inhibitor resistance in influenza: a clinical perspectiveSemantic proximity Read ↗

Molecular mechanisms of influenza virus resistance to neuraminidase inhibitors.Semantic proximity Read ↗

Zanamivir-resistant influenza viruses with a novel neuraminidase mutation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.