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Article

Target protectors reveal dampening and balancing of Nodal agonist and antagonist by miR-430.

Science (New York, N.Y.) - 12 Oct 2007

Choi Wen-Yee, Giraldez Antonio J, Schier Alexander F

Abstract excerpt

MicroRNAs (miRNAs) repress hundreds of target messenger RNAs (mRNAs), but the physiological roles of specific miRNA-mRNA interactions remain largely elusive. We report that zebrafish microRNA-430 (miR-430) dampens and balances the expression of the transforming growth factor-beta (TGF-beta) Nodal...

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Identifiers

PMID: 17761850
DOI: 10.1126/science.1147535

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17761850-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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