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Article

Reduced expression of INK4a/ARF genes in stem-like sphere cells from rat sarcomas.

Biochemical and biophysical research communications - 26 Oct 2007

Fujii Hiromasa, Honoki Kanya, Tsujiuchi Toshifumi, Kido Akira, Yoshitani Kazuhiro, Mori Toshio, Takakura Yoshinori

Abstract excerpt

The presence of cancer stem cells, in both hematopoietic and solid malignancies, has been recently linked to their pathogenesis. We aimed to identify the characteristics and stem-like properties of sphere-colony forming cells in rat osteosarcoma and malignant fibrous histiocytoma cell lines. The results showed that both cell lines possessed an ability to form spherical, clonally expanding colonies in...

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Source

Identifiers

PMID: 17761140
DOI: 10.1016/j.bbrc.2007.08.067

Genes

STAT3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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