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Article

Human primary bone sarcomas contain CD133 <sup>+</sup> cancer stem cells displaying high tumorigenicity <i>in vivo</i>

8 Mar 2011

Abstract excerpt

This study aimed to identify, isolate, and characterize cancer stem cells from human primary sarcomas. We performed cytometric analyses for stemness and differentiation antigens, including CD29, CD34, CD44, CD90, CD117, and CD133, on 21 human primary sarcomas on the day of surgery. From sarcoma biopsies, we obtained 2 chondrosarcoma-stabilized cell lines and 2 osteosarcoma stabilized cell lines, on which sphere...

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PMID: 21385990
DOI: 10.1096/fj.10-179036

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