Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Aldh1 Expression and Activity Increase During Tumor Evolution in Sarcoma Cancer Stem Cell Populations

13 Jun 2016

Abstract excerpt

Tumors evolve from initial tumorigenic events into increasingly aggressive behaviors in a process usually driven by subpopulations of cancer stem cells (CSCs). Mesenchymal stromal/stem cells (MSCs) may act as the cell-of-origin for sarcomas, and CSCs that present MSC features have been identified in sarcomas due to their ability to grow as self-renewed floating spheres (tumorspheres). Accordingly, we previously...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Renal and related cancers
Share to Sarcoma Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27292183
DOI: 10.1038/srep27878

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Aldh1 Expression and Activity Increase During Tumor Evolution in Sarcoma Cancer Stem Cell PopulationsPMID 27292183Read ↗

Aldehyde Dehydrogenase 1, a Potential Marker for Cancer Stem Cells in Human SarcomaSemantic proximity Read ↗

The Concept of Cancer Stem Cells: Elaborating on ALDH1B1 as an Emerging Marker of Cancer ProgressionSemantic proximity Read ↗

Possible involvement of stem-like populations with elevated ALDH1 in sarcomas for chemotherapeutic drug resistanceSemantic proximity Read ↗

The ALDH1+ subpopulation of the human NMFH-1 cell line exhibits cancer stem-like characteristicsSemantic proximity Read ↗

Prospective identification of tumorigenic osteosarcoma cancer stem cells in OS99‐1 cells based on high aldehyde dehydrogenase activitySemantic proximity Read ↗

Cancer stem-like cells stay in a plastic state ready for tumor evolutionSemantic proximity Read ↗

Tumor heterogeneity and cancer stem cell paradigm: Updates in concept, controversies and clinical relevanceSemantic proximity Read ↗

Cancer stem cells in solid tumors: an overview and new approaches for their isolation and characterizationSemantic proximity Read ↗

Tumor heterogeneity from the viewpoint of pathologists.Semantic proximity Read ↗

Tumorigenic Cell Reprogramming and Cancer Plasticity: Interplay between Signaling, Microenvironment, and EpigeneticsSemantic proximity Read ↗

Cancer Stem Cells in Soft-Tissue SarcomasSemantic proximity Read ↗

Cancer stem cells: problems for therapy?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.