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Sphere-forming cell subpopulations with cancer stem cell properties in human hepatoma cell lines

14 Jun 2011

Abstract excerpt

BACKGROUND: Cancer stem cells (CSCs) are regarded as the cause of tumor formation and recurrence. The isolation and identification of CSCs could help to develop novel therapeutic strategies specifically targeting CSCs. METHODS: Human hepatoma cell lines were plated in stem cell conditioned culture system allowed for sphere forming. To evaluate the stemness characteristics of spheres, the self-renewal,...

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PMID: 21669008
DOI: 10.1186/1471-230x-11-71

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