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Article

Analogy between sphere forming ability and stemness of human hepatoma cells

27 Sept 2010

Abstract excerpt

Increasing evidence suggests that cancers contain a small subset of cancer-initiating cells, so-called cancer stem cells (CSCs) that are capable of regenerating a tumor after chemoradiation therapy. Sphere forming ability is known to be one of properties of CSCs, but the significance remains unclear. The present study focused on sphere formation of human hepatoma cells in three-dimensional culture in order to...

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Identifiers

PMID: 20878104
DOI: 10.3892/or_00000966

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