Article
Transcriptional activity of the long control region in human papillomavirus type 33 intratype variants.
Virology journal - 17 Jul 2023
Gyöngyösi Eszter, László Brigitta, Szalmás Anita, Kónya József, Veress György
Abstract excerpt
BACKGROUND: High-risk human papillomaviruses (HPVs) are responsible for the development of cervical and other anogenital cancers. Intratype sequence variants of certain high-risk HPV types (e.g. 16, 18 and 31) are thought to have different oncogenic potential, partly due to nucleotide sequence variation in the viral long control region (LCR). The LCR has an important role in the regulation of viral replication...
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