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Ovarian Cancer G Protein Coupled Receptor 1, a New Metastasis Suppressor Gene in Prostate Cancer

28 Aug 2007

Abstract excerpt

BACKGROUND: Metastasis is a process by which tumors spread from primary organs to other sites in the body and is the major cause of death for cancer patients. The ovarian cancer G protein-coupled receptor 1 (OGR1) gene has been shown to be expressed at lower levels in metastatic compared with primary prostate cancer tissues. METHODS: We used an orthotopic mouse metastasis model, in which we injected PC3...

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PMID: 17728215
DOI: 10.1093/jnci/djm107

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