Article
Androgen receptor-independent function of FoxA1 in prostate cancer metastasis.
Cancer research - 15 Jun 2013
Jin Hong-Jian, Zhao Jonathan C, Ogden Irene, Bergan Raymond C, Yu Jindan
Abstract excerpt
FoxA1 (FOXA1) is a pioneering transcription factor of the androgen receptor (AR) that is indispensible for the lineage-specific gene expression of the prostate. To date, there have been conflicting reports on the role of FoxA1 in prostate cancer progression and prognosis. With recent discoveries of recurrent FoxA1 mutations in human prostate tumors, comprehensive understanding of FoxA1 function has become very...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
