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GPCR-Gα13 Involvement in Mitochondrial Function, Oxidative Stress, and Prostate Cancer

28 Jun 2024

Abstract excerpt

genes, respectively, are members of the G12 family of Gα proteins that, along with their associated Gβγ subunits, mediate signaling from specific G protein-coupled receptors (GPCRs). Advanced prostate cancers have increased expression of GPCRs such as CXC Motif Chemokine Receptor 4 (CXCR4), lysophosphatidic acid receptor (LPAR), and protease activated receptor 1 (PAR-1). These GPCRs signal through either the G12...

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PMID: 39000269
DOI: 10.3390/ijms25137162

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