Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

RNAi-mediated knockdown of pituitary tumor- transforming gene-1 (PTTG1) suppresses the proliferation and invasive potential of PC3 human prostate cancer cells

4 Aug 2012

Abstract excerpt

Pituitary tumor-transforming gene-1 (PTTG1) is a proto-oncogene that promotes tumorigenesis and metastasis in numerous cell types and is overexpressed in a variety of human tumors. We have demonstrated that PTTG1 expression was up-regulated in both human prostate cancer specimens and prostate cancer cell lines. For a more direct assessment of the function of PTTG1 in prostate tumorigenesis, RNAi-mediated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Angiogenesis and VEGF in Cancer
Share to Pituitary Gland Disorders and Treatments
Share to TGF-β signaling in diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22872288
DOI: 10.1590/s0100-879x2012007500126

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

RNAi-mediated knockdown of pituitary tumor- transforming gene-1 (PTTG1) suppresses the proliferation and invasive potential of PC3 human prostate cancer cellsPMID 22872288Read ↗

Increased expression of pituitary tumor-transforming gene (PTTG)-1 is correlated with poor prognosis in glioma patientsSemantic proximity Read ↗

Pituitary tumor-transforming gene 1 and endocrine cancers: an up-to-date review through history, current insights and future perspectivesSemantic proximity Read ↗

Pttg1 Promotes Growth of Breast Cancer through P27 Nuclear ExclusionSemantic proximity Read ↗

A Comprehensive Pan-Cancer Analysis for Pituitary Tumor-Transforming Gene 1Semantic proximity Read ↗

Adenovirus-mediated transfer of siRNA against PTTG1 inhibits liver cancer cell growth in vitro and in vivoSemantic proximity Read ↗

PTTG1 Oncogene Promotes Tumor Malignancy via Epithelial to Mesenchymal Transition and Expansion of Cancer Stem Cell PopulationSemantic proximity Read ↗

Multi-omics analysis Identifies PTTG1 as a prognostic biomarker associated with immunotherapy and chemotherapy resistanceSemantic proximity Read ↗

Long non‐coding RNA PRRT3‐AS1 silencing inhibits prostate cancer cell proliferation and promotes apoptosis and autophagySemantic proximity Read ↗

Nuclear Localization of PTTG1 Promotes Migration and Invasion of Seminoma Tumor Through Activation of MMP-2.Semantic proximity Read ↗

Tazarotene-Induced Gene 1 (TIG1) Expression in Prostate Carcinomas and Its Relationship to TumorigenicitySemantic proximity Read ↗

Ectopic expression of PTTG1/securin promotes tumorigenesis in human embryonic kidney cells.Semantic proximity Read ↗

PTTG and PBF Functionally Interact with p53 and Predict Overall Survival in Head and Neck Cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.