Article

Anti-Metastatic Effect of GV1001 on Prostate Cancer Cells; Roles of GnRHR-Mediated Gαs-cAMP Pathway and AR-YAP1 Axis

2021-07-08

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Gonadotropin-releasing hormone receptor (GnRHR) transmits its signal via two major Gα-proteins, primarily Gαq and Gαi. However, the precise mechanism underlying the functions of Gαs signal in prostate cancer cells is still unclear. We have previously identified that GV1001, a fragment of the human telomerase reverse transcriptase, functions as a biased GnRHR lig...

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Literature Corpus work: 141800ab-28ee-515c-b325-984d84ee5b44
DOI: 10.21203/rs.3.rs-552002/v2

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Anti-Metastatic Effect of GV1001 on Prostate Cancer Cells; Roles of GnRHR-Mediated Gαs-cAMP Pathway and AR-YAP1 AxisDOI 10.21203/rs.3.rs-552002/v2Read

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