Article
No association between dopamine D4 receptor gene -521 C/T polymorphism and tardive dyskinesia in schizophrenia.
Neuropsychobiology - 1 Jan 2007
Lee Heon-Jeong, Kang Seung-Gul, Choi Jung-Eun, Paik Jong-Woo, Kim Yong-Ku, Kim Seung-Hyun, Lee Min-Soo, Joe Sook-Haeng, Jung In-Kwa, Kim Leen
Abstract excerpt
Tardive dyskinesia (TD) is a long-term adverse effect of antipsychotics. We evaluated whether a candidate functional polymorphism of the dopamine D4 receptor (DRD4) gene is associated with drug-induced TD in 209 Korean schizophrenic patients with TD (n = 83) and without TD (n = 126) who were matched for antipsychotic drug exposure and other relevant variables. There was no significant association of the genotype...
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