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Article

The combination of homozygous MTHFR 677T and angiotensin II type-1 receptor 1166C variants confers the risk of small-vessel-associated ischemic stroke.

Journal of molecular neuroscience : MN - 1 Jan 2007

Szolnoki Zoltan, Maasz Anita, Magyari Lili, Horvatovich Katalin, Farago Bernadett, Somogyvari Ferenc, Kondacs Andras, Szabo Mihaly, Bodor Anita, Hadarits Ferenc, Melegh Bela

Abstract excerpt

Previous studies have suggested that both angiotensin II type-1 receptor (AT1R) 1166C and methylenetetrahydrofolate reductase (MTHFR) 677T variants can have disadvantageous effects on the small-vessel circulation under certain conditions. The purpose of this study was to analyze the possible consequences of the simultaneous distribution of these two genetic variants in different types of ischemic stroke. The...

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Share to Receptor, Angiotensin, Type 1

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Source

Identifiers

PMID: 17726226
DOI: 10.1385/jmn:31:03:201

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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