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Article

Gene polymorphisms of the renin-angiotensin-aldosterone system and the risk of ischemic stroke: a role of the A1166C/AT1 gene variant.

Journal of hypertension - 1 Nov 2004

Rubattu Speranza, Di Angelantonio Emanuele, Stanzione Rosita, Zanda Bastianina, Evangelista Anna, Pirisi Angelo, De Paolis Paola, Cota Linda, Brunetti Ercole, Volpe Massimo

Abstract excerpt

OBJECTIVE: The role of the renin-angiotensin-aldosterone system (RAAS) genes on predisposition to develop stroke, a multifactorial and polygenic cardiovascular trait, is still under investigation. In the present study we characterized the contributory role of RAAS genes in the susceptibility to develop ischemic stroke in humans. METHODS: Allele and genotype frequencies of RAAS genes were characterized in a...

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Identifiers

PMID: 15480097
DOI: 10.1097/00004872-200411000-00015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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