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Article

Angiotensin II type-1 receptor A1166C polymorphism is associated with increased risk of ischemic stroke in hypertensive smokers.

Journal of molecular neuroscience : MN - 1 Jan 2006

Szolnoki Zoltán, Havasi Viktória, Talián Gábor, Bene Judit, Komlósi Katalin, Somogyvári Ferenc, Kondacs András, Szabó Mihály, Fodor Lajos, Bodor Anita, Melegh Béla

Abstract excerpt

Recent observations revealed a novel role of angiotensin-converting enzyme 2 and the angiotensin II type-1 receptor (AT1R) in lung injury, thereby extending knowledge about the functions of the angiotensin system. Angiotensin II, whose target is the AT1R, is a potent vasoconstrictor. Accordingly, an imbalance leading to enhanced activity of the angiotensin II-AT1R axis is postulated to contribute to both...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16691016
DOI: 10.1385/JMN:28:3:285
PMCID: PMC7090441

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Angiotensin II type-1 receptor A1166C polymorphism is associated with increased risk of ischemic stroke in hypertensive smokers.PMID 16691016Read ↗

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The combination of homozygous MTHFR 677T and angiotensin II type-1 receptor 1166C variants confers the risk of small-vessel-associated ischemic stroke.Semantic proximity Read ↗

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Angiotensin II type 1 receptor (AT1) gene A1166C is associated with the risk of hypertension.Semantic proximity Read ↗

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