Article
Silent SNPs: impact on gene function and phenotype.
Pharmacogenomics - 1 Aug 2007
Komar Anton A
Abstract excerpt
Evaluation of: Kimchi-Sarfaty C, Oh JM, Kim IW et al.: A 'silent' polymorphism in the MDR1 gene changes substrate specificity. Science 315, 525-528 (2007) [1] . Individuals carrying silent SNPs in the MDR1 gene encoding P-glycoprotein sometimes reveal altered P-glycoprotein pharmacokinetics. Ther...
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