Article
Trafficking of siderophore transporters in Saccharomyces cerevisiae and intracellular fate of ferrioxamine B conjugates.
Traffic (Copenhagen, Denmark) - 1 Nov 2007
Froissard Marine, Belgareh-Touzé Naïma, Dias Marylène, Buisson Nicole, Camadro Jean-Michel, Haguenauer-Tsapis Rosine, Lesuisse Emmanuel
Abstract excerpt
We have studied the intracellular trafficking of Sit1 [ferrioxamine B (FOB) transporter] and Enb1 (enterobactin transporter) in Saccharomyces cerevisiae using green fluorescent protein (GFP) fusion proteins. Enb1 was constitutively targeted to the plasma membrane. Sit1 was essentially targeted to the vacuolar degradation pathway when synthesized in the absence of substrate. Massive plasma membrane sorting of Sit1...
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