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Article

The siderophore iron transporter of Candida albicans (Sit1p/Arn1p) mediates uptake of ferrichrome-type siderophores and is required for epithelial invasion.

Infection and immunity - 1 Sept 2002

Heymann Petra, Gerads Michaela, Schaller Martin, Dromer Francoise, Winkelmann Günther, Ernst Joachim F

Abstract excerpt

The human fungal pathogen Candida albicans contains a close homologue of yeast siderophore transporters, designated Sit1p/Arn1p. We have characterized the function of SIT1 in C. albicans by constructing sit1 deletion strains and testing their virulence and ability to utilize a range of siderophores and other iron complexes. sit1 mutant strains are defective in the uptake of ferrichrome-type siderophores including...

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Identifiers

PMID: 12183576
DOI: 10.1128/IAI.70.9.5246-5255.2002
PMCID: PMC128288

Genes

SIT1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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