Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The alloimmune response to the human platelet antigen-1a is not related to maternal-fetal killer immunoglobulinlike receptor/HLA-Cw combinations.

Transfusion - 1 Dec 2007

Valentin Nathalie, Gagne Katia, Kerdudou Nolwenn, Hallé Liliane, Kaplan Cécile, Killie Mette Kjaer, Skogen Bjorn, Muller Jean-Yves, Bignon Jean-Denis

Abstract excerpt

BACKGROUND: Human platelet antigen (HPA)-1a fetomaternal alloimmune thrombocytopenia, responsible in the most severe cases for fetal or neonatal intracranial hemorrhages leading to death or survival with neurologic sequelae, was shown to be restricted to the human leukocyte antigen (HLA) Class II DRB3*0101-encoded molecule. Whereas more than 90 percent of alloimmunized mothers display the DRB3*0101 allele, the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, Human Platelet
Share to Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HLA Antigens

Share to Integrin beta3

Share to Isoantibodies

Share to Maternal-Fetal Exchange

Share to Pregnancy

Share to Receptors, KIR

Source

Identifiers

PMID: 17714418
DOI: 10.1111/j.1537-2995.2007.01450.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The alloimmune response to the human platelet antigen-1a is not related to maternal-fetal killer immunoglobulinlike receptor/HLA-Cw combinations.PMID 17714418Read ↗

Maternal antibodies against paternal class I human leukocyte antigens are not associated with foetal and neonatal alloimmune thrombocytopeniaSemantic proximity Read ↗

Foetal and neonatal alloimmune thrombocytopenia - The role of the HLA-DRB3*01:01 allele for HPA-1a-immunisation and foetal/neonatal outcome.Semantic proximity Read ↗

HLA‐DRB3*01:01 is a predictor of immunization against human platelet antigen‐1a but not of the severity of fetal and neonatal alloimmune thrombocytopeniaSemantic proximity Read ↗

Compound heterozygosity of HLA-DRB3*01:01 and HLA-DRB4*01:01 as a potential predictor of fetal neonatal alloimmune thrombocytopenia.Semantic proximity Read ↗

Severe fetomaternal alloimmune thrombocytopenia due to anti-human platelet antigen (HPA)-1a in a mother with a rare and silenced ITGB3*0101 (GPIIIa) allele.Semantic proximity Read ↗

Maternal HLA genotyping is not useful for predicting severity of fetal and neonatal alloimmune thrombocytopenia.Semantic proximity Read ↗

Antenatal management of fetal and neonatal alloimmune thrombocytopenia: Integration of clinical history and maternal HLA-DRB3*01:01 genotyping in clinical decision-making.Semantic proximity Read ↗

Assessment of human platelet antigen (HPA)-1a alloimmunisation in women identified at increased risk for foetal and neonatal alloimmune thrombocytopaenia (FNAIT): a prospective, natural history studySemantic proximity Read ↗

Immunity at maternal–fetal interface: KIR / HLA (Allo)recognition*Semantic proximity Read ↗

HPA-1a antibodies in FNAIT do not distinguish αvβ3 from αIIbβ3, and bind inactive integrins more strongly than active integrinsSemantic proximity Read ↗

Alloantibodies against low-frequency human platelet antigens do not account for a significant proportion of cases of fetomaternal alloimmune thrombocytopenia: evidence from 1054 cases.Semantic proximity Read ↗

Noninvasive fetal genotyping of human platelet antigen-1a.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.