Article
Rat wct mutation induces a hypo-mineralization form of amelogenesis imperfecta and cyst formation in molar teeth.
Cell and tissue research - 1 Oct 2007
Osawa Masaru, Kenmotsu Shin-Ichi, Masuyama Taku, Taniguchi Kazuyuki, Uchida Takashi, Saito Chikara, Ohshima Hayato
Abstract excerpt
Our previous findings have demonstrated that the rat autosomal-recessive mutation, whitish chalk-like teeth (wct), induces enamel defects resembling those of human amelogenesis imperfecta (AI) in continuously growing incisor teeth. The present study clarifies the effect of the wct mutation on the morphogenesis and calcification of rat molar teeth. Formalin-fixed maxillae obtained from animals aged 4-30 days were...
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