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SCPP Gene Evolution and the Dental Mineralization Continuum

1 Jun 2008

Abstract excerpt

Many genes critical to vertebrate skeletal mineralization are members of the secretory calcium-binding phosphoprotein (SCPP) gene family, which has evolved by gene duplication from a single ancestral gene. In humans, mutations in some of these SCPP genes have been associated with various diseases related to dentin or enamel hypoplasia. Recently, systematic searches for SCPP genes of various species have allowed...

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PMID: 18502959
DOI: 10.1177/154405910808700608

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