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Article

Rat wct mutation prevents differentiation of maturation-stage ameloblasts resulting in hypo-mineralization in incisor teeth.

Histochemistry and cell biology - 1 Sept 2007

Osawa Masaru, Kenmotsu Shin, Masuyama Taku, Taniguchi Kazuyuki, Uchida Takashi, Saito Chikara, Ohshima Hayato

Abstract excerpt

A recent study provided genetic and morphological evidence that rat autosomal-recessive mutation, whitish chalk-like teeth (wct), induced tooth enamel defects resembling those of human amelogenesis imperfecta (AI). The wct locus maps to a specific interval of rat chromosome 14 corresponding to human chromosome 4q21 where the ameloblastin and enamelin genes exist, although these genes are not included in the wct...

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PMID: 17636316
DOI: 10.1007/s00418-007-0297-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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