Article
An immortalized rat ventral mesencephalic cell line, RTC4, is protective in a rodent model of stroke.
Cell transplantation - 1 Jan 2007
Harvey B K, Chen G J, Schoen C J, Lee C T, Howard D B, Dillon-Carter O, Coggiano M, Freed W J, Wang Y, Hoffer B J, Sanchez J F
Abstract excerpt
One therapeutic approach to stroke is the transplantation of cells capable of trophic support, reinnervation, and/or regeneration. Previously, we have described the use of novel truncated isoforms of SV40 large T antigen to generate unique cell lines from several primary rodent tissue types. Here we describe the generation of two cell lines, RTC3 and RTC4, derived from primary mesencephalic tissue using a...
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