Article
Vg1 has specific processing requirements that restrict its action to body axis patterning centers.
Developmental biology - 1 Oct 2007
Thomas John Terrig, Moos Malcolm
Abstract excerpt
Unlike most transforming growth factor-beta (TGF-beta) superfamily members, Vg1 has been shown not to produce gross phenotypic alterations in Xenopus embryos when overexpressed by mRNA injection. Experiments with artificial chimeric constructs and a recently identified second allele of Vg1 suggest that this may be due to unusually stringent requirements for proteolytic processing. We provide biological and...
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