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Article

Induction of dorsal mesoderm by soluble, mature Vg1 protein

1 Jul 1995

Abstract excerpt

Mesoderm induction during Xenopus development has been extensively studied, and two members of the transforming growth factor-beta family, activin beta B and Vg1, have emerged as candidates for a natural inducer of dorsal mesoderm. Heretofore, analysis of Vg1 activity has relied on injection of hybrid Vg1 mRNAs, which have not been shown to direct efficient secretion of ligand and, therefore, the mechanism of...

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PMID: 7635059
DOI: 10.1242/dev.121.7.2155

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