Article
Quasispecies and the implications for virus persistence and escape.
Clinical and diagnostic virology - 15 Jul 1998
Domingo E
Abstract excerpt
BACKGROUND: In the 1970s Manfred Eigen and colleagues proposed a new model of molecular evolution to explain adaptability and rapid evolution of simple replicons, as those that probably populated the earth at the onset of life. This model of evolution placed emphasis on mutant generation, to the...
Topics
- Animals
- Evolution, Molecular
- Genetic Variation
- Humans
- RNA Virus Infections
- RNA Viruses
