Article
Evolution of peroxisome proliferator-activated receptor gamma alternative splicing.
Frontiers in bioscience (Elite edition) - 1 Jun 2010
Dou Tonghai, Xu Jiaxi, Gao Yuan, Gu Jianlei, Ji Chaoneng, Xie Yi, Zhou Yan
Abstract excerpt
Peroxisome proliferator-activated receptor gamma (PPAR gamma) plays an important role in the control of energy balance and lipid and glucose homeostasis. Different transcript variants were investigated not only in human but also in other vertebrates. To look into the evolutionary changes of these variants, we analyzed the genomic sequences of PPAR gamma genes from several vertebrate species, as well as their mRNA...
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