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Article

Complement regulatory genes and hemolytic uremic syndromes.

Annual review of medicine - 1 Jan 2008

Kavanagh David, Richards Anna, Atkinson John

Abstract excerpt

Hemolytic uremic syndrome is a triad of microangiopathic hemolytic anemia, thrombocytopenia, and acute renal failure. It is one of a group of conditions termed the thrombotic microangiopathies, which are characterized by prominent endothelial cell injury. It may be diarrheal-associated or atypical (aHUS). Evidence for a pathogenic role of the alternative pathway of complement was first suggested in 1974....

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Identifiers

PMID: 17705684
DOI: 10.1146/annurev.med.59.060106.185110

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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