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Article

The additive effect of individual genes in predicting risk of knee osteoarthritis.

Annals of the rheumatic diseases - 1 Jan 2008

Valdes A M, Doherty M, Spector T D

Abstract excerpt

OBJECTIVE: Genetic factors are important determinants of osteoarthritis (OA) but most individual genetic associations appear relatively modest. We aimed to answer whether carrying several genetic variants associated with knee OA could result in a greater risk of OA. METHODS: Genotypes for 36 single nucleotide polymorphisms (SNPs) in 17 candidate genes previously associated with OA were analysed in 298 men and 305...

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PMID: 17704066
DOI: 10.1136/ard.2007.075838

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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