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Article

Association of ADAMTS-5 gene polymorphisms with the susceptibility to knee osteoarthritis in a Chinese Han population.

Journal of orthopaedic surgery and research - 27 Aug 2024

Gao Shan, Jia Menglong, Wang Jingwei, Sun Qiankun, Liu Fangxiu, Yu Longtan, Guo YanXing, Li Nianhu, Wei Lei

Abstract excerpt

BACKGROUND: Osteoarthritis (OA) is the most prevalent type of arthritis and the main reason for progressive disability in middle-aged and older people. Studies of candidate genes may provide a novel insight and treatment strategy for knee osteoarthritis (KOA). The aim of this study was to investigate the relationship between KOA susceptibility and single-nucleotide polymorphism (SNP) of the ADAMTS-5 gene....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39192347
DOI: 10.1186/s13018-024-05023-0
PMCID: PMC11348706

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