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Article

HTR2C haplotypes and antipsychotics‐induced weight gain: X‐linked multimarker analysis

13 Aug 2007

Abstract excerpt

UNLABELLED: The 5HT2C receptor (HTR2C) has been hypothesized to represent an important modulator in feeding behavior. Evidence was based on the observation that knock-out mice for the HTR2C receptor gene develop obesity and that many antipsychotics (AP) with potent HTR2C antagonism may induce weight gain in susceptible individuals. Pharmacogenetic studies focusing either on the Cys23Ser polymorphism or on the...

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PMID: 17702092
DOI: 10.1002/hup.868

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HTR2C haplotypes and antipsychotics‐induced weight gain: X‐linked multimarker analysisPMID 17702092Read ↗

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