Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Targeting the AKT protein kinase for cancer chemoprevention

1 Aug 2007

Abstract excerpt

The AKT protein kinase transduces signals from growth factors and oncogenes to downstream targets that control crucial elements in tumor development. The AKT pathway is one of the most frequently hyperactivated signaling pathways in human cancers. Available data are reviewed herein to support targeting the AKT kinase for cancer prevention. This review will present data to show that AKT is up-regulated in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Mechanisms and Therapy
Share to PI3K/AKT/mTOR signaling in cancer
Share to Protein Degradation and Inhibitors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17699713
DOI: 10.1158/1535-7163.mct-07-0120

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Targeting the AKT protein kinase for cancer chemopreventionPMID 17699713Read ↗

AKT in cancer: new molecular insights and advances in drug developmentSemantic proximity Read ↗

PI3K-independent AKT activation in cancers: a treasure trove for novel therapeutics.Semantic proximity Read ↗

The Akt pathway in oncology therapy and beyond (Review)Semantic proximity Read ↗

Perturbations of the AKT signaling pathway in human cancer.Semantic proximity Read ↗

AKT: A Central Node in Complex Signaling CascadesSemantic proximity Read ↗

Akt: a key transducer in cancerSemantic proximity Read ↗

Handicapping the Race to Develop Inhibitors of the Phosphoinositide 3-Kinase/Akt/Mammalian Target of Rapamycin PathwaySemantic proximity Read ↗

The PKB/AKT pathway in cancer.Semantic proximity Read ↗

The Pathogenic Role of PI3K/AKT Pathway in Cancer Onset and Drug Resistance: An Updated ReviewSemantic proximity Read ↗

Targeting the PI3K-Akt pathway in human cancerSemantic proximity Read ↗

Research progress on the PI3K/AKT signaling pathway in gynecological cancer (Review)Semantic proximity Read ↗

Modulation of AKT Pathway-Targeting miRNAs for Cancer Cell Treatment with Natural ProductsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.