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Article

Mining complex genotypic features for predicting HIV-1 drug resistance.

Bioinformatics (Oxford, England) - 15 Sept 2007

Saigo Hiroto, Uno Takeaki, Tsuda Koji

Abstract excerpt

MOTIVATION: Human immunodeficiency virus type 1 (HIV-1) evolves in human body, and its exposure to a drug often causes mutations that enhance the resistance against the drug. To design an effective pharmacotherapy for an individual patient, it is important to accurately predict the drug resistance based on genotype data. Notably, the resistance is not just the simple sum of the effects of all mutations....

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Identifiers

PMID: 17698858
DOI: 10.1093/bioinformatics/btm353

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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