Article
Predicting HIV drug resistance using weighted machine learning method at target protein sequence-level.
Molecular diversity - 1 Aug 2021
Cai Qihang, Yuan Rongao, He Jian, Li Menglong, Guo Yanzhi
Abstract excerpt
Acquired immune deficiency syndrome (AIDS) is a fatal disease caused by human immunodeficiency virus (HIV). Although 23 different drugs have been available, the treatment of AIDS remains challenging because the virus mutates very quickly which can lead to drug resistance. Therefore, predicting drug resistance before treatment is crucial for individual treatments. Here, based on HIV target protein sequence...
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