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Article

Control of inward rectifier K channel activity by lipid tethering of cytoplasmic domains.

The Journal of general physiology - 1 Sept 2007

Enkvetchakul Decha, Jeliazkova Iana, Bhattacharyya Jaya, Nichols Colin G

Abstract excerpt

Interactions between nontransmembrane domains and the lipid membrane are proposed to modulate activity of many ion channels. In Kir channels, the so-called "slide-helix" is proposed to interact with the lipid headgroups and control channel gating. We examined this possibility directly in a cell-f...

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Identifiers

PMID: 17698595
DOI: 10.1085/jgp.200709764
PMCID: PMC2151642

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17698595-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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