Article
[Effect of antibiotics on 5'-inosinic acid biosynthesis by a Brevibacterium ammoniagenes mutant].
Prikladnaia biokhimiia i mikrobiologiia - 1 Jan 2000
Balabushevich M I, Kazarinova L A
Abstract excerpt
The effect of streptomycin, erythromycin, kanamycin and penicillin on the biosynthesis of 5'-inosinic acid (IMP) by the mutant strain Brevibacterium ammoniagenes was studied. It has been found that the efficiency of antibiotic action depends not only in its concentration but on the age of the culture. When the antibiotics were introduced into the culture broth at the beginning of fermentation, they inhibited the...
Topics
- Anti-Bacterial Agents
- Brevibacterium
- Dose-Response Relationship, Drug
- Fermentation
- Inosine Monophosphate
- Inosine Nucleotides
- Mutation
- Stimulation, Chemical
- Time Factors