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Article

A novel STK11 germline mutation in two siblings with Peutz-Jeghers syndrome complicated by primary gastric cancer.

Clinical genetics - 1 Jan 2005

Shinmura K, Goto M, Tao H, Shimizu S, Otsuki Y, Kobayashi H, Ushida S, Suzuki K, Tsuneyoshi T, Sugimura H

Abstract excerpt

Patients with Peutz-Jeghers syndrome (PJS) are known to be at risk of gastric cancer (GC), and the STK11 gene is a susceptibility gene for PJS. However, as no cases of PJS with GC in which a STK11 germline mutation has been identified have ever been reported and other susceptibility genes have al...

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Source

Identifiers

PMID: 15617552
DOI: 10.1111/j.1399-0004.2005.00380.x

Genes

STK11
CDH1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15617552-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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