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Genomic and functional analyses of <i>MUTYH</i> in Japanese patients with adenomatous polyposis

7 May 2008

Abstract excerpt

The present study was undertaken to elucidate germ line mutations of the base excision repair gene, MUTYH, in Japanese patients with adenomatous polyposis. We screened germ line mutations of adenomatous polyposis coli (APC) gene and MUTYH in 66 Japanese patients with adenomatous polyposis. APC was screened by the protein truncation test, while MUTYH was screened by polymerase chain reaction-based single-strand...

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PMID: 18422726
DOI: 10.1111/j.1399-0004.2008.00998.x

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