Article
Polymorphisms and haplotypes of the gene encoding the estrogen-metabolizing CYP19 gene in Korean women: no association with advanced-stage endometriosis.
Journal of human genetics - 1 Jan 2007
Hur Sung Eun, Lee Sara, Lee Ji Young, Moon Hye-Sung, Kim Hyung Lae, Chung Hye Won
Abstract excerpt
A variety of factors affect the development of endometriosis, including hormonal status and genetic factors. The growth of endometriosis is stimulated by local estrogen production in conjunction with circulating estrogen. The CYP19 gene encodes a steroid aromatase that catalyses the conversion of C-19 androgens to estrogens. This study investigated whether polymorphisms of the CYP19 gene are associated with the...
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