Article
CYP19 gene variant confers susceptibility to endometriosis-associated infertility in Chinese women.
Experimental & molecular medicine - 27 Jun 2014
Wang Ledan, Lu Xiaosheng, Wang Danhan, Qu Wanglei, Li Wenju, Xu Xiaowen, Huang Qiusui, Han Xueying, Lv Jieqiang
Abstract excerpt
An aromatase encoded by the CYP19 gene catalyzes the final step in the biosynthesis of estrogens, which is related to endometriosis development. To assess the association of CYP19 gene polymorphisms with the risks of endometriosis, chocolate cysts and endometriosis-related infertility, a case-control study was conducted in Chinese Han women by recruiting 225 healthy control females, 146 patients with...
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